Newly identified C/EBPγ protein links cancer cell plasticity and DNA repair

A research team has identified the transcription factor C/EBPγ as a novel regulator that simultaneously promotes epithelial-mesenchymal transition (EMT) and DNA double-strand break repair in lung adenocarcinoma cells. The findings, published in Cell Death Discovery, provide new insights into how cancer cells acquire aggressive features and resistance to anticancer treatments.